… the role of INSTNs in viral endocytosis by interaction with signalling pathways. INSTN-2 …
enhancing ubiquitylation of EGFR by ubiquitin E3 ligase Cbl due to growth factor stimulation [25]. …

… Epidermal growth factor receptor (EGFR) is a critical regulator … step for endocytosis as
mutations of EGFR ubiquitination sites … Intersectin is one of the possible candidates. As a scaffold-…

… the receptor, a signal that targets EGFR to degradation in lysosomes (4–6). Interestingly, CME
is also regulated by ubiquitination of endocytic … sprouty 2, intersectin disrupts the sprouty 2-…

… by interacting with an endocytic scaffold protein Intersectin (11)… differences in epidermal
growth factor (EGF) receptor trafficking … We examined the ubiquitination of endogenous WASH in …

… in vivo intersect with this diverse signaling, focusing on receptor … considered, with the epidermal
growth factor receptor (EGFR) as … accompanied by ubiquitylation, tagging it for lysosomal …

… to trigger downstream signalling pathways in a growth factor-… also being at the intersection
between autophagy and intrinsic … endocytosis to rapidly internalise selected (eg, ubiquitylated) …

… Epidermal growth factor receptor (EGFR) takes centre stage … rules that regulate EGFR
intracellular function intersect with and … ubiquitination, impacting both EGFR and its signalling and …

… growth factor-α (TGF-α)-mediated epidermal growth factor … , thereby preventing basal
endocytosis and degradation of … of protein ubiquitination in regulating cytokine signaling and IFN-…

… Receptor tyrosine kinase epidermal growth factor receptor (… various signal pathways through
mediating the ubiquitination … of CBL in signal transduction and receptor internalization in …

… lies at the intersection of multiple signaling pathways that enhance … several EGFR (epidermal
growth factor receptor)-like repeats … Blocking the ubiquitination and trans-endocytosis of the …